Potassium-sparing diuretics such as triamterene and amiloride in antihypertensive drugs work by blocking sodium channels, reducing the absorption of sodium ions while inhibiting the secretion of potassium ions, thereby producing a sodium-excreting, potassium-retaining diuretic effect. Bananas are high in potassium, and when taken concurrently with potassium-sparing diuretics, they may cause hyperkalemia. In certain cases, this can lead to inhibitory effects on systems such as the cardiovascular system, resulting in noticeable symptoms such as numbness, muscle paralysis, drowsiness, and fatigue.
Therefore, it is recommended to wait at least two hours between consuming bananas and taking antihypertensive drugs.