Men Beware of Five Types of "Sterility-Causing" Medications
I. Drugs that Directly Inhibit Spermatogenesis.
Such as dithiopyr, which is a type of insecticide, but it also has the effect of inhibiting sperm production; other drugs, such as nitrofurans, alkylating agents used for chemotherapy, and gossypol recently extracted from cottonseed, all have a powerful inhibitory effect on testicular sperm production.
II. Drugs that Affect Sperm Maturation.
The use of anti-androgen compounds such as medroxyprogesterone acetate and chlorohydrin drugs, although they have little effect on testicular sperm function, these drugs have a direct effect on sperm produced by the testes, preventing them from maturing and losing their fertilization ability.
III. Hormonal Drugs.
The use of drugs such as estrogen, progesterone, and testosterone propionate can inhibit the secretion of pituitary gonadotropins, which in turn can inhibit the sperm production function of the testes.
IV. Drugs that Affect Ejaculation.
Drugs used to treat hypertension, such as guanethidine and thioridazine, can reduce the amount of ejaculate in users, or even cause anejaculation. Some drugs can inhibit the ejaculatory reflex, delaying ejaculation, such as meprobamate and clomipramine.
V. Many topical drugs, such as surfactants, organometallic compounds (such as phenylmercuric acetate), and weak acids, have a direct spermicidal effect.
If such topical drugs are frequently used to treat female reproductive tract diseases, such as vaginal suppositories, it will inevitably affect fertility.