Clinical findings have shown that when a patient with hyperlipidemia takes one tablet of Meijiangliao with a glass of grapefruit juice, the lipid-lowering effect is equivalent to taking 12 to 15 tablets of the same medication with water. This can lead to muscle pain and even kidney damage. Grapefruit should not be taken with these medications.
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Some patients taking the antihistamine terfenadine may experience dizziness, palpitations, arrhythmia, and other mild symptoms if they eat grapefruit or drink grapefruit juice. In severe cases, it may lead to sudden death.
Other medications that can have adverse interactions with grapefruit include cyclosporine, caffeine, calcium channel blockers, and cisapride. The potential for interaction with medication can last for 24 hours after consuming a glass of grapefruit juice. Therefore, patients who are taking medication, especially the elderly, should avoid eating grapefruit or drinking grapefruit juice.
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